Antimicrobial Compounds for Medical

TekniPlex Healthcare has introduced antimicrobial medical compounds that can be utilized to produce a number of patient-contact products, including catheters, connectors, gas hoses, injection systems such as syringes, and needle-free injectors such as pens. Now available for formulation and production, the products can incorporate silver ion technology proven to drastically reduce the risk of contamination due to bacteria buildup.

TekniPlex is offering PVC and TPE compounds formulated with silver ion technology. To develop its antimicrobial series of products, TekniPlex Healthcare integrates the silver ion additives, which have natural antimicrobial properties, with its broad array of current medical grade flexible and rigid PVC compounds, or its medical grade Cellene TPE compounds. Unlike disinfectants that last just a few hours, formulating a medical product with antimicrobial compounds provides protection throughout the product's lifespan.

When challenged by the presence of bacteria on a surface, the release of silver ions inhibit a bacteria cellʼs ability to reproduce. The silver ions enter the cell through its outer layer, block enzymes to prevent the cell from generating energy, and disrupt its DNA, thereby removing its ability to split and create a duplicate of itself. The technology is effective against a wide range of bacteria from E. coli and Salmonella to antibiotic-resistant bacteria like Methicillin Resistant Staphylococcus Aureus (MRSA) and Vancomycin-resistant enterococci (VRE).

Given the perils of healthcare facility-borne infections, the antimicrobial solutions have considerable potential to benefit hospitals and other care centers, the company says. Products made with silver-containing compounds can achieve 80% bacteria reduction in 15 minutes, and are over 99.9% effective after two hours. Tested to ISO 22196:2011 standards, TekniPlex Healthcare’s medical grade compounds were shown to reduce E. coli and staphylococcus aureus (S. aureus) by over 99.9% in 24 hours.